I don't think it will be a mismatch, Floyd is a survivor. If he doesn't get knocked out he will stay in the fight and try to cope with Manny's hand speed and left handed style. But in the end around the tenth round he will retire in the corner.
I don't know if it's the shoulder roll will not working against a southpaw as much as Floyds inexperiance that is keeping this fight from happening but Floyd needs to agree to this fight or retire.
Bradley first went to the UK and won the WBC by beating Witter and then won the WBO title by beating Holt. Alexander now has the WBC and IBF titles. It's not so unimaginable this bout is for the Ring title. It's either leading to a big money fight at welterweight or an unification with Khan, either way we would benefit.
Adamek is a light heavyweight/cruiserweight that barely got by Michael Grant. He has no power at heavyweight. What champion wouldn't want a payday like this.
Either of them lacks the endurance to remained focused the full twelve and when you consider Khan's best opponent was Maidana who could barely beat DeMarcus Corley in Argentina, anythng is possible. But Judah is past his prime, has trouble fightinng at 140 and Amir is in his prime, I would say the odds are with Khan.