I haven't tried hydroxycut yet. I use the Ripped Fuel- Definition. I am a little sensitive to caffeine so usually I take like 2/3 or 3/4 a capsule per workout.
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How good is Hydroxycut harcore for losing weight
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I've taken Hydroxycut and it seemed to work a bit in the beginning (as far as increasing my metabolism) but my body seemed to adjust to it and now it dont work for **** on me. I'm thinking of trying NO-Xplode...if anyone has heard anything about it, any feedback would be appreciated.
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Originally posted by Phantasm View PostI've taken Hydroxycut and it seemed to work a bit in the beginning (as far as increasing my metabolism) but my body seemed to adjust to it and now it dont work for **** on me. I'm thinking of trying NO-Xplode...if anyone has heard anything about it, any feedback would be appreciated.
Supplements that reportedly increase nitric oxide levels within the body are currently being marketed as powerful muscle builders. The marketers of these supplements claim they increase nitric oxide levels within muscle tissue and a dramatic increase in muscle size, strength is experienced. Other claims also include an increase in fast-twitch muscle fiber strength, endurance, power output, and load capacity from taking these supplements. These reported benefits are quite specific, so I decided to scan the literature for the scientific evidence that supports these claims.
Nitric Oxide ? what is it?
Nitric oxide is a colorless, free radical gas commonly found in tissues of all mammals (it?s also prepared commercially by passing air through an electric arc). Biologically, nitric oxide has been shown to be an important neuro-messenger in a number of vertebrate signal transduction processes. Nitric oxide is used in medical treatment; for example, nitroglycerin ameliorates the pain of angina by supplying nitric oxide to the blood vessels that supply the heart. The popular drug Viagra controls erection by regulating nitric oxide in the penile cartilage chamber.
The Research and the Claims
I don?t know where the marketers obtained their literature on nitric oxide. It looks like they are using the same journals as the companies selling Myostatin inhibitors ? Alice in Wonderland. Although nitric oxide acts as a cell-to-cell communicator for certain metabolic functions, muscle growth is not one of them. After a review of the available literature I cannot find any research that remotely indicates increasing nitric oxide levels plays a part in increasing protein synthesis, contractile strength or any other biochemical pathway that may lead to increases in muscle mass.
For a company to claim their supplement increases ?fast-twitch? muscle strength, the promoters must have instigated or funded some kind of research that involved biopsy procedures and histochemical analyses to extract, assesses and identify these particular muscle fibers from animals or humans, before and after supplementation. However, I could find no documentation (either on their web sites or via a literature scan) that details these findings, only the marketing claims. As far as I?m aware, there is zero scientific evidence supporting the notion that nitric oxide supplements increase ?fast-twitch? muscle strength.
There also appears to be no evidence whatsoever that shows increasing nitric oxide levels enhances endurance, power output, and load capacity.
Arginine alpha-ketogluterate is the ?active? ingredient reported by one company that sells this type of supplement. It is claimed that this compound increases and maintains a constantly high level of nitric oxide in muscle. Nitric oxide is synthesized within the body using the amino acid arginine, the energy cyclic substrate NADPH, and oxygen. Nitric oxide diffuses freely across membranes but it is a transient signaling molecule. Nitric oxide is by nature, a highly reactive gas that has an extremely short life ? less than a few seconds. While there is a lot of research on the effects of nitric oxide, there is no research that shows supplementation with arginine alpha-ketogluterate increases or sustains nitric oxide levels in any human or animal organs.
Can you imagine, a supplement that ?creates dramatic increases in muscle size, strength, endurance, power output, and load capacity?, but not a single study to support these claims. Nothing new here. Unfortunately, this is typical sports nutrition marketing bull****. It's sad, misleading, and shows you just what these companies think of the intelligence level of their target market.
When new products burst onto the market, you the consumer can cut through the advertising hype quite easily. Simply ask the supplement company making the claims to "show you the research". A reference is a start, but the actual research study is particularly what your after. You want to see the study, the protocol, the outcome and the University at which the study was conducted. In the present case, you want to see a study showing were this supplement actually increased nitric oxide above a control group, and you want to see the data that demonstrates an increase in lean muscle mass, significantly more than the group without elevated nitric oxide levels.
The fact is, there is no science supporting any of the claims made for so-called nitric oxide supplements. There is no science showing they have any effect on nitric oxide levels and certainly no science showing in effects on muscle growth or increased performance.
Ask yourself why there is no research to support these companies? wild claims. The simple answer is that research is expensive, make believe products are not. Research provides evidence, fraudulent supplement marketing only delivers hype. It?s far more financially rewarding to sell hype than to produce effective supplements backed by science.
One promoter of a nitric oxide supplement claims to have ?brought creatine supplementation to the market? and that their supplement is ?the perfected version of creatine?. I?m not sure which market is being referred to but creatine has been used as a supplement for over 40 years. And in NO way are nitric oxide supplements a ?perfected version of creatine?. They are nothing like creatine. While creatine is backed by a wealth of research, nitric oxide supplements do not have a shred of scientific evidence that justifies their effectiveness as a bodybuilding supplements.
Bottom line, money spent on these products is money flushed down the toilet.
Read the Real Science
1. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992 6(12):3051-64.
2. Mayer B; Hemmens B. Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 1997 22(12):477-81.
3. Janabi N; Chabrier S; Tardieu M. Endogenous nitric oxide activates prostaglandin F2 alpha production in human microglial cells but not in astrocytes: a study of interactions between eicosanoids, nitric oxide, and superoxide anion (O2-) regulatory pathways. J Immunol 1996 1;157(5):2129-35.
4. Esposito C; Cozzolino A; Porta R; Mariniello L; Buommino E; Morelli F; Metafora V; Metafora S. Protein SV-IV promotes nitric oxide production not associated with apoptosis in murine macrophages. Eur J Cell Biol 2002 81(4):185-96.
5. Eckmann L; Laurent F; Langford TD; Hetsko ML; Smith JR; Kagnoff MF; Gillin FD. Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen Giardia lamblia. J Immunol 2000 1;164(3):1478-87.
6. Kelly RA; Smith TW. Nitric oxide and nitrovasodilators: similarities, differences, and interactions. Am J Cardiol 1996 30;77(13):2C-7C.
7. Stryer L. Biochemistry 4th Ed. Freeman & Co. 1997.
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Originally posted by Phantasm View PostI've taken Hydroxycut and it seemed to work a bit in the beginning (as far as increasing my metabolism) but my body seemed to adjust to it and now it dont work for **** on me. I'm thinking of trying NO-Xplode...if anyone has heard anything about it, any feedback would be appreciated.
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Originally posted by parrinkinpau View Posti am starting to taking it i heard is pretty good i have to lose 30 pounds.
any advise
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I've lost 42lbs since xmas. Stop looking for easy ways to lose weight and run mother ****ers. Go out and run a few mile a day instead of sittin here TALKING about how you want to lose weight.
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Originally posted by sjfou View Posti wouldnt waste my time or $$$ with a NO supp - pretty irrelevant for a boxer. Pretty irrelevant for anyone actually... Read below:
Supplements that reportedly increase nitric oxide levels within the body are currently being marketed as powerful muscle builders. The marketers of these supplements claim they increase nitric oxide levels within muscle tissue and a dramatic increase in muscle size, strength is experienced. Other claims also include an increase in fast-twitch muscle fiber strength, endurance, power output, and load capacity from taking these supplements. These reported benefits are quite specific, so I decided to scan the literature for the scientific evidence that supports these claims.
Nitric Oxide ? what is it?
Nitric oxide is a colorless, free radical gas commonly found in tissues of all mammals (it?s also prepared commercially by passing air through an electric arc). Biologically, nitric oxide has been shown to be an important neuro-messenger in a number of vertebrate signal transduction processes. Nitric oxide is used in medical treatment; for example, nitroglycerin ameliorates the pain of angina by supplying nitric oxide to the blood vessels that supply the heart. The popular drug Viagra controls erection by regulating nitric oxide in the penile cartilage chamber.
The Research and the Claims
I don?t know where the marketers obtained their literature on nitric oxide. It looks like they are using the same journals as the companies selling Myostatin inhibitors ? Alice in Wonderland. Although nitric oxide acts as a cell-to-cell communicator for certain metabolic functions, muscle growth is not one of them. After a review of the available literature I cannot find any research that remotely indicates increasing nitric oxide levels plays a part in increasing protein synthesis, contractile strength or any other biochemical pathway that may lead to increases in muscle mass.
For a company to claim their supplement increases ?fast-twitch? muscle strength, the promoters must have instigated or funded some kind of research that involved biopsy procedures and histochemical analyses to extract, assesses and identify these particular muscle fibers from animals or humans, before and after supplementation. However, I could find no documentation (either on their web sites or via a literature scan) that details these findings, only the marketing claims. As far as I?m aware, there is zero scientific evidence supporting the notion that nitric oxide supplements increase ?fast-twitch? muscle strength.
There also appears to be no evidence whatsoever that shows increasing nitric oxide levels enhances endurance, power output, and load capacity.
Arginine alpha-ketogluterate is the ?active? ingredient reported by one company that sells this type of supplement. It is claimed that this compound increases and maintains a constantly high level of nitric oxide in muscle. Nitric oxide is synthesized within the body using the amino acid arginine, the energy cyclic substrate NADPH, and oxygen. Nitric oxide diffuses freely across membranes but it is a transient signaling molecule. Nitric oxide is by nature, a highly reactive gas that has an extremely short life ? less than a few seconds. While there is a lot of research on the effects of nitric oxide, there is no research that shows supplementation with arginine alpha-ketogluterate increases or sustains nitric oxide levels in any human or animal organs.
Can you imagine, a supplement that ?creates dramatic increases in muscle size, strength, endurance, power output, and load capacity?, but not a single study to support these claims. Nothing new here. Unfortunately, this is typical sports nutrition marketing bull****. It's sad, misleading, and shows you just what these companies think of the intelligence level of their target market.
When new products burst onto the market, you the consumer can cut through the advertising hype quite easily. Simply ask the supplement company making the claims to "show you the research". A reference is a start, but the actual research study is particularly what your after. You want to see the study, the protocol, the outcome and the University at which the study was conducted. In the present case, you want to see a study showing were this supplement actually increased nitric oxide above a control group, and you want to see the data that demonstrates an increase in lean muscle mass, significantly more than the group without elevated nitric oxide levels.
The fact is, there is no science supporting any of the claims made for so-called nitric oxide supplements. There is no science showing they have any effect on nitric oxide levels and certainly no science showing in effects on muscle growth or increased performance.
Ask yourself why there is no research to support these companies? wild claims. The simple answer is that research is expensive, make believe products are not. Research provides evidence, fraudulent supplement marketing only delivers hype. It?s far more financially rewarding to sell hype than to produce effective supplements backed by science.
One promoter of a nitric oxide supplement claims to have ?brought creatine supplementation to the market? and that their supplement is ?the perfected version of creatine?. I?m not sure which market is being referred to but creatine has been used as a supplement for over 40 years. And in NO way are nitric oxide supplements a ?perfected version of creatine?. They are nothing like creatine. While creatine is backed by a wealth of research, nitric oxide supplements do not have a shred of scientific evidence that justifies their effectiveness as a bodybuilding supplements.
Bottom line, money spent on these products is money flushed down the toilet.
Read the Real Science
1. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992 6(12):3051-64.
2. Mayer B; Hemmens B. Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 1997 22(12):477-81.
3. Janabi N; Chabrier S; Tardieu M. Endogenous nitric oxide activates prostaglandin F2 alpha production in human microglial cells but not in astrocytes: a study of interactions between eicosanoids, nitric oxide, and superoxide anion (O2-) regulatory pathways. J Immunol 1996 1;157(5):2129-35.
4. Esposito C; Cozzolino A; Porta R; Mariniello L; Buommino E; Morelli F; Metafora V; Metafora S. Protein SV-IV promotes nitric oxide production not associated with apoptosis in murine macrophages. Eur J Cell Biol 2002 81(4):185-96.
5. Eckmann L; Laurent F; Langford TD; Hetsko ML; Smith JR; Kagnoff MF; Gillin FD. Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen Giardia lamblia. J Immunol 2000 1;164(3):1478-87.
6. Kelly RA; Smith TW. Nitric oxide and nitrovasodilators: similarities, differences, and interactions. Am J Cardiol 1996 30;77(13):2C-7C.
7. Stryer L. Biochemistry 4th Ed. Freeman & Co. 1997.
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BTW, dont take my word for it, listen to an expert:
Ephedrine and Boxing Training
By Ross Enamait - Published in 2002
Note – This article was written prior to the FDA’s ban on ephedra
I have received several inquiries regarding the use of ephedrine-based supplements to enhance the intensity and weight loss effects of a boxing routine. Many supplements combine ephedrine with caffeine as a means to increase energy. Common examples include Ripped Fuel, Ripped Force, and Xenadrine RFA-1. Recently, several ephedrine products have come under harsh criticism by the Food and Drug Administration (FDA).
Ephedrine is a central nervous system stimulant and decongestant that is effective for relieving bronchial asthma. It is derived from plants of the genus Ephedra. It comes from the Chinese herb Ma Huang. Ephedrine has been used for centuries as both a stimulant and bronchodilator. Recently, ephedrine has been marketed to athletes and those looking to lose weight, based on its ability to trigger energy bursts while causing a reduced appetite.
Unfortunately, since 1993 the FDA states that at least 17 people have died and 800 made ill by dietary supplements containing ephedrine. The FDA recommends a maximum daily ephedrine dose of 24 milligrams. Each supplement should contain no more than 8 milligrams of ephedrine per serving and should not be taken continuously for over a 1-week period. The side effects of ephedrine include elevated blood pressure, irregular heartbeat, stroke, dizziness, restlessness, irritability, and headache. Combinations of ephedrine and caffeine cause side effects substantially worse than those from either compound alone. Most energy enhancement products that contain ephedrine also contain caffeine.
Due to the widespread criticism of ephedrine-based supplements, many product manufacturers have created similar products that do not contain ephedrine. An example is the new ephedrine-free Xenadrine EFX. These products claim to provide increased energy without the dangers of ephedrine. These replacement products often increase caffeine to make up for the lack of ephedrine.
Do these products provide any benefits to the aspiring boxer? After all, boxing is perhaps the most physically demanding sport. Conditioning often means the difference between winning and losing. In addition, a boxer must stay within a specific weight range when competing. Are these products beneficial to fighters? I will emphatically answer both of these questions with a very stern NO. These products are NOT beneficial to competitive boxers.
It is worth repeating that boxing is perhaps the most physically demanding sport of all. Physical conditioning almost always plays a factor in the outcome of a bout. When two equally skilled fighters compete, the deciding factor is often conditioning. Unfortunately, there are no magic pills to create a champion. Boxing is a very difficult sport. Those not willing to train hard and make the appropriate sacrifices are quickly weeded out.
There are no shortcuts in this sport. Boxing has very little to do with luck and a whole lot to do with hard work. By relying on a substance to provide energy, you become dependent both physically and mentally. You begin to think that without the product you cannot succeed. This mindset is detrimental to young boxers. Boxing is a mental sport where you must enter the ring with confidence. You must learn to rely and depend on your skills and training, not on a pill or energy drink.
Consider past greats like Rocky Marciano and Muhammad Ali who came up in an era before these products were available. These extraordinary athletes were able to perform at levels previously unknown without the use of "energy" supplements. These great boxers are real life examples that hard work is all that is required to achieve optimum physical and mental condition.
Furthermore, both the International Olympic Committee and National Collegiate Athletic Association ban the use of ephedrine-based products. The Professional Boxing Control Regulations of 1996 also lists ephedrine as a banned substance. For this reason, you will not be able to compete with these products at Olympic or professional competitions. Get used to relying on your hard work. The dependencies that you will develop for energy supplements will become difficult to overcome.
I can tell you from experience that these products do not provide any worthwhile advantages. As a youngster, I tried products such as Ripped Fuel without results. Boxing is performed at an anaerobic pace where combinations are fired in rapid succession. These products cause your heart to beat too fast.
I strongly recommend avoiding these products when boxing. There is no substitute for hard work and proper nutrition. Eat smart and train hard and you will be ready to perform.
www.rossboxing.com
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