AICAR-Hi Tech PED Must you idiots have never herd of>
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And that's why I made this thread to show that blood testing and not just urine tests are needed In Sports. There are to many idiots on here that think that urine is good enough.Last edited by Wapacman; 04-08-2011, 05:23 PM.Comment
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yeah... No
aicar is detectable by urinalysis and the test has been used by wada since 2009.
So this thread and the op has been one embarrassing massive FAILURE.Comment
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I get it that u have no ***in clue about pharmacokinetics. There are other holes u can poke in this article. This is not one idiot!Comment
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hey genius, guess what? IT IS DETECTABLE BY URINE TESTS!
AICA ribonucleotide or AICAR (aminoimidazole carboxamide ribonucleotide) is an intermediate in the generation of inosine monophosphate, which acts as an AMP-activated protein kinase agonist.[1] It stimulates glucose uptake and increases the activity of p38 mitogen-activated protein kinases α and β in skeletal muscle tissue,[2] as well as suppressing apoptosis by reducing production of reactive oxygen compounds inside the cell.[3]
In 2008, researchers at the Salk Institute discovered that AICAR given to experimental mice significantly improves their performance in endurance-type exercise, apparently by converting fast-twitch muscle fibers to the more energy-efficient, fat-burning, slow-twitch type. They also looked at the administration of GW 501516 (also called GW1516) in combination with AICAR. Given to mice that did not exercise, this combination activated 40% of the genes that were turned on when mice were given GW1516 and made to exercise. This suggests it may be possible to obtain some of the benefits of exercising without actually exercising.[4] Because of the enhanced endurance effects, this could potentially be used by athletes to enhance their performance. One of the lead researchers from this study has developed a urine test to detect it and has made the test available to the International Olympic Committee, and the World Anti-Doping Agency has added AICAR to the prohibited list from 2009 onwards.[5]Comment
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Ha, Im a floyd fan but i got to appreciate this post.
well done...Comment
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nah. *****s will just ignore this one even though it's safer, non-invasive and cheaper. you'd think that it's supposed to be good news for *****s who advocates a clean sport. naah. they want blood tests, these experts.... lol.hey genius, guess what? IT IS DETECTABLE BY URINE TESTS!
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One of the lead researchers from this study has developed a urine test to detect it and has made the test available to the International Olympic Committee, and the World Anti-Doping Agency has added AICAR to the prohibited list from 2009 onwards.[5]Comment
@ "Hi Tech PED Must you idiots have never herd of>"
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