Everything you need to know about Xylocaine

[Easy-E]

im a pharmacist student... i know the legitimacy of the site

true story

there is a wealth of information on that website about that product.
Like I said, you didnt even look at it, or read it, just made a comment.

[DarthVoid]

[BlackHat]

Im sure everybody needs some more info on this substance, so I looked it up...

http://www.drugs.com/pro/xylocaine.html
Xylocaine (lidocaine HCl Injection, USP) is a sterile nonpyrogenic solution of an antiarrhythmic agent administered intravenously by direct injection.

Xylocaine Injection is composed of an aqueous solution of lidocaine hydrochloride. Lidocaine HCl (C14H22N2O•HCl) is chemically designated acetamide, 2-(diethylamino)-N-(2, 6-dimethylphenyl)-, monohydrochloride and is represented by the following structural formula:
pH adjusted to 5.0 to 7.0 with sodium hydroxide and/or hydrochloric acid. Single use container. Solution does not contain preservatives

Xylocaine - Clinical Pharmacology
Mechanism of Action and Electrophysiology

Studies of the effects of the****utic concentrations of lidocaine on the electrophysiological properties of mammalian Purkinje fibers have shown that lidocaine attenuates phase 4 diastolic depolarization, decreases automaticity, and causes a decrease or no change in excitability and membrane responsiveness. Action potential duration and effective refractory period of Purkinje fibers are decreased, while the ratio of effective refractory period to action potential is increased. Action potential duration and effective refractory period of ventricular muscle are also decreased. Effective refractory period of the AV node may increase, decrease or remain unchanged, and atrial effective refractory period is unchanged. Lidocaine raises the ventricular fibrillation threshold. No significant interactions between lidocaine and the autonomic nervous system have been described and consequently, lidocaine has little or no effect on autonomic tone.

Clinical electrophysiological studies with lidocaine have demonstrated no change in sinus node recovery time or sinoatrial conduction time. AV nodal conduction time is unchanged or shortened, and His-Purkinje conduction time is unchanged

...lots more info on the website.

Fact is it enhances Floyds performance inside the ring.

[- v e t -]

there is a wealth of information on that website about that product.
Like I said, you didnt even look at it, or read it, just made a comment.

false


true story

even more so.... its a matter of "how" you read and interpret as compared to just having "text"

[DarthVoid]

im a pharmacist student... i know the legitimacy of the site

true story

Xylocaine is heavily regulated because it has serious side-effects:

Systemic exposure to excessive quan****** of lidocaine mainly result in central nervous system (CNS) and cardiovascular effects – CNS effects usually occur at lower blood plasma concentrations and additional cardiovascular effects present at higher concentrations, though cardiovascular collapse may also occur with low concentrations. CNS effects may include CNS excitation (nervousness, tingling around the mouth (also known as circumoral paraesthesia), tinnitus, tremor, dizziness, blurred vision, seizures) followed by depression, and with increasingly heavier exposure: drowsiness, loss of consciousness, respiratory depression and apnoea). Cardiovascular effects include hypotension, bradycardia, arrhythmias, and/or cardiac arrest – some of which may be due to hypoxemia secondary to respiratory depression.

Adverse drug reactions (ADRs) associated with the use of intravenous lidocaine are similar to toxic effects from systemic exposure above. These are dose-related and more frequent at high infusion rates (≥3 mg/minute). Common ADRs include: headache, dizziness, drowsiness, confusion, visual disturbances, tinnitus, tremor, and/or paraesthesia. Infrequent ADRs associated with the use of lidocaine include: hypotension, bradycardia, arrhythmias, cardiac arrest, muscle twitching, seizures, coma, and/or respiratory depression.

http://en.wikipedia.org/wiki/Lidocaine#Adverse_drug_reactions

http://www.drugs.com/pro/xylocaine.html

[deuce_drop]

illegal or not, it helps the fighter out by limiting pain, so there for it is a PED and falls into that category in this regard...........

which is a hypocrisy with floyds level playing field........

floyd can take something to ease pain but his opponent doesnt because his opponent isnt taking it......... makes sense if you're floyd looking to have everything in your favor...

[- v e t -]

Xylocaine is heavily regulated because it has serious side-effects:

wikipedia and drugs.com???

i've stayed neutral in this discussion regarding fighters... and will remain doing so

but that doesnt change the lack of intelligence displayed by boxingscene posters

[CaRnAgEViOLaToR]

Err..it's only a painkiller for his messed up hand. I don't know what the big deal is?

[- v e t -]

Err..it's only a painkiller.

tell that to everyone that overdosed on oxycontin

[DarthVoid]

wikipedia and drugs.com???

i've stayed neutral in this discussion regarding fighters... and will remain doing so

but that doesnt change the lack of intelligence displayed by boxingscene posters

can you give me a more comprehensive site then showing the side-effects of lidocaine abuse?