How effective is taking HGH two weeks before a fight?

The same applies to Mayweather and Pacquiao. My thing is the 14 days clause may never need to be put into place considering the blood testing may not even reach 14 days prior to the fight. Again, according to Tygart, there was "No Need" to continue blood testing for Mosley and Mayweather up to the 18 days prior to the fight. If something similar applies to Floyd and Pacquiao where no further blood tests are needed after such and such date, is the USADA now looked at as a bad testing protocol since people assume Pacquiao will juice up in 12-14 days even if he's tested with blood and urine immediately after the fight? Seems as if even if the USADA does its job to its fullest capacity that there will still be question marks over Pacquiao. LMAO nice sig http://tinyurl.com/2bgtdod

People keep saying that Pac should take the random tests up to the fight night. But i have yet to read of any good reason why the tests should be taken so close to the fight, when from my point of view, taking any kind of drug, PED or taking HGH so close to the fight would be pointless and actually counter-productive. Floyd's not complaining.

you guys are still trying to figure it out?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830221/ Erythropoietin (EPO) Rationale Erythropoietin leads to the production of red blood cells. Since these carry oxygen to active muscles, one would consider enhanced endurance performance because of the additional flux of oxygen. Physiology EPO is a circulating glycosylated protein hormone that is the principal regulator of erythropoiesis. It is produced primarily by the kidney inversely related to the concentration of O2 in the blood. Following administration, there is a direct relationship between haemoglobin levels and increased performance following administration of rHuEPO in rats and humans . Methods used in doping include hypoxia and hypoxia-mimetics. One such method is to train at altitude; however, one cannot necessarily train as hard as at lower altitude because of hypoxic-mediated fatigue. Variations on this theme include living at altitude and training at sea level or sleeping in a tent or chamber with diminished oxygen tension (at lower altitude) and training at the same elevation. These methods are not considered doping. Performance Enhancement rHuEPO and its follow-on biological relatives can provide an effective mechanism to stimulate erythropoiesis as noted above; however, the baseline hematocrit increases and may rise even more to dangerous levels, likely due to dehydration, in athletes during and after training and competition. The rheology of blood changes exponentially as the hematocrit rises above 55% and accelerates even more rapidly as it rise above 60%. Adverse Events Deaths in competitive cyclists have been directly linked to changes in the flow properties of blood, as the hematocrit rises. There are no studies of rHuEPO, or its related proteins in child or adolescent athletes, but theoretically the responses should be no different from older adolescents or young adults. The major issues are those that relate to increased hematocrit- sluggish blood flow in the small vessels of critical organs and pulmonary emboli. Detection Detection of EPO and some of the follow-on drugs is performed on urine sample using gel electrophoresis. Each of the individual compounds (drugs) has a "signature" of glycosylation sites making the detection quite precise . Edit: For the people blindly talking about EPO although they have no knowledge of it. If I'm not mistaken, According to the USADA, Urine is tested just as much as blood and closer to the fight as well as the night of the fight, right?

how effective is anything 14 days before? youd get more benefit from a 5 hour energy drink than you would of roiding up the day of. and thats without saying it can be cycled out that quickly

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830221/ Erythropoietin (EPO) Rationale Erythropoietin leads to the production of red blood cells. Since these carry oxygen to active muscles, one would consider enhanced endurance performance because of the additional flux of oxygen. Physiology EPO is a circulating glycosylated protein hormone that is the principal regulator of erythropoiesis. It is produced primarily by the kidney inversely related to the concentration of O2 in the blood. Following administration, there is a direct relationship between haemoglobin levels and increased performance following administration of rHuEPO in rats and humans . Methods used in doping include hypoxia and hypoxia-mimetics. One such method is to train at altitude; however, one cannot necessarily train as hard as at lower altitude because of hypoxic-mediated fatigue. Variations on this theme include living at altitude and training at sea level or sleeping in a tent or chamber with diminished oxygen tension (at lower altitude) and training at the same elevation. These methods are not considered doping. Performance Enhancement rHuEPO and its follow-on biological relatives can provide an effective mechanism to stimulate erythropoiesis as noted above; however, the baseline hematocrit increases and may rise even more to dangerous levels, likely due to dehydration, in athletes during and after training and competition. The rheology of blood changes exponentially as the hematocrit rises above 55% and accelerates even more rapidly as it rise above 60%. Adverse Events Deaths in competitive cyclists have been directly linked to changes in the flow properties of blood, as the hematocrit rises. There are no studies of rHuEPO, or its related proteins in child or adolescent athletes, but theoretically the responses should be no different from older adolescents or young adults. The major issues are those that relate to increased hematocrit- sluggish blood flow in the small vessels of critical organs and pulmonary emboli. Detection Detection of EPO and some of the follow-on drugs is performed on urine sample using gel electrophoresis. Each of the individual compounds (drugs) has a "signature" of glycosylation sites making the detection quite precise . Edit: For the people blindly talking about EPO although they have no knowledge of it.

how many times can you blood dope in 14days? that can't be detected by Random Urine testing and a Blood test that night after the fight.

thats correct, but the FIGHT DIDNT KNOW testing had been stop. therefore they arent going to chance cheating The same applies to Mayweather and Pacquiao. My thing is the 14 days clause may never need to be put into place considering the blood testing may not even reach 14 days prior to the fight. Again, according to Tygart, there was "No Need" to continue blood testing for Mosley and Mayweather up to the 18 days prior to the fight. If something similar applies to Floyd and Pacquiao where no further blood tests are needed after such and such date, is the USADA now looked at as a bad testing protocol since people assume Pacquiao will juice up in 12-14 days even if he's tested with blood and urine immediately after the fight? Seems as if even if the USADA does its job to its fullest capacity that there will still be question marks over Pacquiao.

you pretty sure? how about you go read Victor Conte's article on the subject well from the articles i read, the effects are rarely noticable less than 14 days and may require up to 42 days

the fact is they can still cheat. like you said it is a risk a fighter can make.

what we are trying to prove is that with a random blood test up to the 14day before the fight and 1 blood immediately with Random urine testing should be enough to scary anyone trying to cheat with no guarantee of wining it is not worry it.

when blood doping - properly cycled- its supposed to be out of your system by the time you perform. so his body is supposed to be clear of the drugs before the fight even starts. so what good is a test going to do after the fight? i was pretty sure that isn't how it works with EPO, any articles?

Since HGH has been ruled out. Then the random BLOOD testing up to 2wk before the fight and 1 BLOOD testing after the fight PLUS Unlimited Urine testing should be enough to detect EPO if that is what a lot of floyd fans are concerned. And Blood doping is to much of a gamble with no guarantee of securing victory in a fight. besides HGH, certain kinds of EPO, Blood Transfusions, but i love how you write it off as too dangerous, it's up to the individual what they're willing to risk to have an advantage. then why may i ask WHY did usada stop BLOOD testing 18 days before the fight if there is a posibility that MOSELY OR FLOYD ARE BLOOD DOPING? Did they know the tests had stopped? No. were they expecting them at any time? Yes, I don't know why people refuse to see the difference between the USADA choosing to stop the tests and a fighter that is being tested making that choice, and how a conflict of interest the concept is.

i think hes blood doping, so he can be on a number of things such as EPO and others. things that can be hidden in urine by using masking agents but pacquiao is allowing blood tests after the fight, surely he'd have to have the EPO in his system during fight night for it to be of any use

First of all, there is no doubt that it takes less than 24 hours to hide HGH (according to Conte). Secondly, there is also a BIG possibility that using PEDS or HGH can help in training in that it can conceivably allow a fighter to train longer and harder and thus give him more strength, stamina, endurance during a fight. That being said, let us just say FOR THE SAKE OF CONVERSATION, that Pac is indeed taking HGH, and if floyd jr. agrees to the 14 day window, he takes that opportunity to take HGH, with the intention of improving his training. How can this actually help him train when at this point in time, he would be winding down his training? It is common knowledge in the athletic world that an athlete must not exert himself/herself close to the time of their performance. This is to prevent overtraining and allow the body to heal so that when the time to fight/perform comes, the athlete is in top shape. Note though that i'm a simple layman and am in no way an expert in PEDS, HGH or such and i'm not pretending to be one. I just have a couple of questions i want answered and hopefully someone would be willing to adequately answer them. Take some, fight your mum and find out. Floyd by TKO

you are damn right. but here is the difference. Floyd WANTS random blood and urine test with no cut off and asking for pac to agree to it, pac DOESNT want random blood and urine with no cut off...well hes down with random urine but not random blood so what does that tell to you? seems like hes got something to hide to me But on the flipside, the random blood testing obviously doesn't state what exact time cut off there is, and basing it off Mayweather vs Mosley's blood testing, theirs ended 18 days prior to the fight (which Tygart himself stated) with the urine testing being conducted up to days prior to the fight and immediately after (urine and blood). Let's just say that for example the blood testing goes forth and then we find out the blood testing for Pac and Mayweather ends around the same time give or take? Do we now automatically blame the USADA for not testing Pacquiao closer to the fight, or do we just rely on the USADA's testing measures regardless of a "14 day" clause being put in (which may not even be met technically to how the tests ultimately will run)? Who's right or wrong in that situation being the testing protocol seems to have been the biggest deal with the negotiations?

then why may i ask WHY did usada stop BLOOD testing 18 days before the fight if there is a posibility that MOSELY OR FLOYD ARE BLOOD DOPING?

please give link

Since HGH has been ruled out. Then the random BLOOD testing up to 2wk before the fight and 1 BLOOD testing after the fight PLUS Unlimited Urine testing should be enough to detect EPO if that is what a lot of floyd fans are concerned. And Blood doping is to much of a gamble with no guarantee of securing victory in a fight.

you are damn right. but here is the difference. Floyd WANTS random blood and urine test with no cut off and asking for pac to agree to it, pac DOESNT want random blood and urine with no cut off...well hes down with random urine but not random blood so what does that tell to you? seems like hes got something to hide to me so what PED do you think he's using that can only be detected via Blood?