What if: How larger gloves affect a fight

[DaveD336]

Settle an argument for me -
If two middleweights, one a power-punching slugger with average hand speed, the other a fast-fisted boxer with average power, were to wear 16 oz gloves instead of 10 oz, in a pro fight, who would have the biggest disadvantage and why?

[DUnknown1]

it all depends, what type of chins and endurance do each one them have