It is possible, John is a pretty good boxer but Gamboa might be to much for him, would be interesting fight though.
Of the 126 pound title holders John would probably be the last guy I would go after if I was Gamboa's team, Cruz and Larios are ripe to be beaten by Gamboa.
Luevano would be a pretty tough challenge also but Gamboa has some impressive physical tools, would be an interesting fight also.
Gamboa is truly a wild card at this point, a chaos factor. He could possibly win by KO in a bum rush performance, but he could just as easily lose a wide UD. When he starts fighting for titles, these questions should begin to be answered.
Gamboa imo is capable to beat anybody, but also is still very vulnerable. His amazing talent, power and agility are elite level, so to asnwer the question.
Yes, he can.
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