Could Mayweather have knocked out Margarito after he fought Cotto?

[KingTito]

I think he could've, but I highly doubt that he would've taken the risk.

[street bully]

Not a chance. Shane was throwing BOMBS I havent seen Shane swing so many hard shots like that for years. Mayweather would have potshoted and moved all night winning a boring UD.

[larryx]

maybe tko cause he wouldve been hitting him at will..but i doubt he wouldve took the risk

[Fenom]

im with you... he's capable of doing it but wouldnt have been throwing bombs like shane was so he wouldnt have risked it

[SickmyDuck]

no........

[catalinul]

Not a chance.
He wouldn't have gone in the ring with him either.

[KESSLER]

Although Mayweather is one of my all time favorites, I don't think he could. Just wouldn't take the risk. Instead, he'd humiliate Margarito, hitting him at will, making him look like a fool.

[DiegoFuego]

Mayweather would have hit Margarito a lot more than Mosley did, but I doubt Margarito's corner would have ever stopped it without a knockdown or something. Mayweather would straight up Gatti him only it would go 12

[god of war]

floyd really is the could have, would have, should have fighter.

[MANGLER]

This is assumin that the punches he took in his fights wit Cintron and Cotto had sumthin to do wit the SSM KO. Maybe that was the case, or maybe SSM was just too damn good for Marg that night. If the former is true, yes he coulda done it, but either way I seriously doubt he woulda had the balls to stay on the attack consistently like SSM did as opposed to peckin him to death for a safety first decision.