By Francisco Salazar

Antonio Margarito (40-8, 27KOs) would like an opportunity to fight Saul 'Canelo' Alvarez (47-1-1, 33KOs).

According to Alvarez, that will not happen. Ever.

While it is a fight that would be realistically difficult to sell to the boxing fan, a clash between Alvarez and Margarito was brought up after Margarito dropped Ramon Alvarez in route to a 10 round split decision victory in Rosarito, Baja California, Mexico on August 13.

Alvarez, who sat ringside for the fight, is the younger brother of Ramon Alvarez.

Margarito has won his last two fights since his four-year hiatus from the ring. Margarito has had numerous surgeries to repair damage to his right eye and orbital bone that occurred in his bouts against Manny Pacquiao and Miguel Cotto.

Alvarez is not interested in a fight with Margarito.

"That will never happen," said Alvarez in a sit-down interview from his training camp in San Diego that aired Saturday night on beIN Sports en Espanol. "My advice to Margarito is to leave the sport. He accomplished a lot in boxing."

"I believe he should leave the sport, not for him but for his family. It's dangerous. He's risking his life in this sport. It's not a game. It's very dangerous. He needs to (retire) for his family."

Alvarez has his sights set on his September 17 clash against Liam Smith at AT&T Stadium in Arlington, Texas. Smith will be defending his WBO junior middleweight title.

No word yet on when Margarito would return to the ring.

Francisco A. Salazar has written for Boxingscene.com since September of 2012 and has covered boxing in Southern California and abroad since 2000. Francisco also covers boxing for the Ventura County (Calif.) Star newspaper, RingTV, and Knockout Nation. He can be reached by email at santio89@yahoo.com or on Twitter at FSalazarBoxing