Manny Pacquiao, the only man to have won world titles in eight weight divisions in a glittering 23-year career, is very eager to get in the ring after a one-year layoff.
"I am ready. Everything is under control," said the 39-year-old Pacquiao. "I am motivated, I am happy and I am hungry."
WBA"regular" welterweight champion Matthysse played up his one-inch height advantage by looking down on Pacquiao as the two came face-to-face for the last time before their 12-round showdown in Kuala Lumpur.
"I am feeling good," Matthysse told AFP. "I made the weight, I'm ready to eat and I'm ready for the battle tomorrow."
Pacquiao is challenging Matthysse at the Axiata Arena, knowing defeat could lower the curtain on one of the greatest careers in boxing history.
But victory for Pacquiao (59-7-2, 38 KOs) would see him become a five-time welterweight world champion and extend his legendary status.
Pacquiao is going for his 60th victory since turning pro in 1995, but despite winning 38 of his first 47 fights by knockout, he has not stopped an opponent in nine years.
But he hopes to end his drought of knockouts, by stopping Matthysse inside the distance.
"Our plan is to move side-to-side, throw a lot of punches and of course, if given a chance, finish the fight early," Pacquiao told The Inquirer.
Matthysse, who is highly regarded as a very dangerous puncher, has finished 36 of his 39 wins inside the distance and took the vacant "regular" WBA belt after an eighth round stoppage of Thailand's Teerachai Sithmorseng in January.
But the last time he faced an opponent of Pacquiao's calibre he was knocked out in the 10th round by Ukrainian super lightweight world champion Viktor Postol in 2015.
Matthysse suffered a fractured left eye socket after taking a big shot from Postol, and that injury that put him out of boxing for 19 months and this is only his third fight since coming back.