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What is Clenbuterol?
Clenbuterol is classified as a sympathomimetic amine, meaning that it is a synthetic subtance analogous to natural neurotransmitters (such as adrenaline) that act on the sympathetic nervous system. Medically, it's value is primarily as a bronchodilator, enabling asthma patients to breathe more easily, but it is most likely to be used by athletes to accelerate weight loss. In simpler terms, Clenbuterol does the following: helps reduce fat mass loss at an accelerated rate, increased protein synthesis and power output (supposedly, on output), and decrease the rate of muscle breakdown while cutting weight. This is a very effective drug for bodybuilding, or in general, any athletes seeking to lose weight while retaining muscle mass and strength. Typically, a cycle will start off at a small concentration, such as 20 mcg, and generally reach a maximum daily limit of 120 mcg over a period of time. A recommended cycle time period is 14 days on, 14 days off (variations exist, of course), with a slow and steady build-up of dosage, due in part as your body slowly builds tolerance. Many people choose to incorporate additional suppliments of taurine and potassium to their diets, in order to combat the side effects of clenbuterol.
What is the half-life of clenbuterol?
Studies have shown that the clenbuterol half-life is approximately 36 hours. A half-life is the period of time required for the concentration amount of drug in the body to be reduced by one-half. We usually consider the half-life of a drug in relation to the amount of the drug in plasma.
How long does it take for clenbuterol to get out of your system?
Drug detection time refers to the length of time during which drug testing will indicate drug elements in the urine, hair, saliva, or blood. This includes the time from when the drug can be first detected to the point in time when you will test clean.
Clenbuterol is excreted from the body in the urine and thus can be detected by analysis using such technology as mass spectrometry. The clenbuterol detection time is 4-6 days after administration, by urine analysis.
VADA Letter about Canelo's positive tests (see link below for image of the letter, or see the summary below):
http://d2s3dt9f4iyeup.cloudfront.net...0fa6179aaa.jpg
Summary
Canelo took two tests:
"Test A" on February 17th in Jalisco, Mexico, which contained 0.6 - 0.8 ng/ml of Clenbuterol and Adverse (??? not sure if this meant there was something else?)
"Test B" on February 20th in Jalisco, Mexico, which contained 0.06 - 0.008 ng/ml of Clenbuterol.
Scientific study on Clenbuterol absorption in humans
https://www.ncbi.nlm.nih.gov/pubmed/4045696
Therapeutic dose (20, 40 and 80 micrograms/man) of clenbuterol hydrochloride, a beta 2-adrenergic stimulant, was orally administered to healthy volunteers, and the unmetabolized drug in plasma and urine was determined by enzyme immunoassay. The plasma levels of clenbuterol reached the maximum value of 0.1, 0.2 and 0.35 ng/ml, respectively, in a dose-dependent manner within 2.5 h, which lasted for over 6 h after the administration. The half-life of clenbuterol in plasma was estimated to be about 35 h. When the drug was orally administered repeatedly to men twice a day, the plasma level reached the plateau within 4 d after the initial administration. At that time, the plasma levels of the unchanged form were 0.2 to 0.3 ng/ml and 0.5 to 0.6 ng/ml at doses of 20 and 40 micrograms/man, respectively. The bound ratio of the drug to plasma protein was estimated to be 89-98% at a single administration of 80 micrograms of the drug. The cumulative urinary excretion of unchanged compound corresponded to about 20% of the administered dose as measured at 72 h following a single oral administration.
What is Clenbuterol?
Clenbuterol is classified as a sympathomimetic amine, meaning that it is a synthetic subtance analogous to natural neurotransmitters (such as adrenaline) that act on the sympathetic nervous system. Medically, it's value is primarily as a bronchodilator, enabling asthma patients to breathe more easily, but it is most likely to be used by athletes to accelerate weight loss. In simpler terms, Clenbuterol does the following: helps reduce fat mass loss at an accelerated rate, increased protein synthesis and power output (supposedly, on output), and decrease the rate of muscle breakdown while cutting weight. This is a very effective drug for bodybuilding, or in general, any athletes seeking to lose weight while retaining muscle mass and strength. Typically, a cycle will start off at a small concentration, such as 20 mcg, and generally reach a maximum daily limit of 120 mcg over a period of time. A recommended cycle time period is 14 days on, 14 days off (variations exist, of course), with a slow and steady build-up of dosage, due in part as your body slowly builds tolerance. Many people choose to incorporate additional suppliments of taurine and potassium to their diets, in order to combat the side effects of clenbuterol.
What is the half-life of clenbuterol?
Studies have shown that the clenbuterol half-life is approximately 36 hours. A half-life is the period of time required for the concentration amount of drug in the body to be reduced by one-half. We usually consider the half-life of a drug in relation to the amount of the drug in plasma.
How long does it take for clenbuterol to get out of your system?
Drug detection time refers to the length of time during which drug testing will indicate drug elements in the urine, hair, saliva, or blood. This includes the time from when the drug can be first detected to the point in time when you will test clean.
Clenbuterol is excreted from the body in the urine and thus can be detected by analysis using such technology as mass spectrometry. The clenbuterol detection time is 4-6 days after administration, by urine analysis.
VADA Letter about Canelo's positive tests (see link below for image of the letter, or see the summary below):
http://d2s3dt9f4iyeup.cloudfront.net...0fa6179aaa.jpg
Summary
Canelo took two tests:
"Test A" on February 17th in Jalisco, Mexico, which contained 0.6 - 0.8 ng/ml of Clenbuterol and Adverse (??? not sure if this meant there was something else?)
"Test B" on February 20th in Jalisco, Mexico, which contained 0.06 - 0.008 ng/ml of Clenbuterol.
Scientific study on Clenbuterol absorption in humans
https://www.ncbi.nlm.nih.gov/pubmed/4045696
Therapeutic dose (20, 40 and 80 micrograms/man) of clenbuterol hydrochloride, a beta 2-adrenergic stimulant, was orally administered to healthy volunteers, and the unmetabolized drug in plasma and urine was determined by enzyme immunoassay. The plasma levels of clenbuterol reached the maximum value of 0.1, 0.2 and 0.35 ng/ml, respectively, in a dose-dependent manner within 2.5 h, which lasted for over 6 h after the administration. The half-life of clenbuterol in plasma was estimated to be about 35 h. When the drug was orally administered repeatedly to men twice a day, the plasma level reached the plateau within 4 d after the initial administration. At that time, the plasma levels of the unchanged form were 0.2 to 0.3 ng/ml and 0.5 to 0.6 ng/ml at doses of 20 and 40 micrograms/man, respectively. The bound ratio of the drug to plasma protein was estimated to be 89-98% at a single administration of 80 micrograms of the drug. The cumulative urinary excretion of unchanged compound corresponded to about 20% of the administered dose as measured at 72 h following a single oral administration.
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