Bookmark Website  | Free Registration  | The Team
The Lounge  | Champions  | The Wire |  Schedule |  Audio  |  Arcade  |  The Top Ten  |  Historical  |  Email  |  Video

More Complete Arthritis Supplement


People accept arthritic disease as a 'natural part of the aging process', but sometimes the pain from osteoarthritis, rheumatoid arthritis, and over 100 other forms of arthritis so intolerable, prompting people to look for effective treatment.

Prescription drugs such as VIOXX, Bextra and Celebrex (arthritic painkillers) - and many other COX-2 inhibitors widely used for arthritic treatment - have been investigated following studies into their negative cardiovascular side effects. VIOXX alone has been linked to around 140,000 cases of coronary heart disease in the US since 1999.

More and more people look for alternative solutions for arthritis pain and more and more people are buying the combination of Glucosamine, Chondroitin Sulfate and MSN, as studies have shown that Glucosamine and Chondroitin help in the repair and maintenance of cartilage.

Both inflammation and oxidative stress function are primary degenerative mechanisms in the development and progression of osteoarthritis. While researchers believe that glucosamine inhibits inflammation and stimulates cartilage cell growth and chondroitin provides cartilage with strength and resilience, specific amino acids is also need for overall impact.

Amino acids are the building blocks that make up protein. Vitamins and minerals will not perform their specific functions effectively if the necessary amino acids are not present.

Three amino acids are critical to antioxidant, anti-inflammatory functions: cysteine, glutathione, and taurine.

Cysteine influences the synthesis of the antioxidant glutathione (GSH), which plays an important role in the inflammatory response by influencing the production of phagocytes.

Taurine acts as a specific scavenger for the hypochlorite ion, a free radical. Adequate levels of taurine naturally limit the degree of inflammation. When taurine is low, the inflammatory response is enhanced, commonly resulting in oxidative stress reactions.

Other amino acid imbalances may also impact the etiology of osteoarthritis - particularly methionine metabolism. Normally, B12 and folate are necessary for the body to metabolize homocysteine to methionine, the essential amino acid the body needs to produce S-adenosylmethionine. Numerous clinical trials have shown that S-adenosylmethionine can greatly reduce degenerative damage and symptoms of osteoarthritis in some patients, including related depression.

Imbalances of amino acids may also signal key deficiencies of vitamins and minerals integral to the musculoskeletal system. Experimental studies show that impaired cartilage structure can be induced by a vitamin B6 deficiency. Vitamin B6 triggers the transformation of the amino acid homocysteine to cystathionine and then to cysteine and its urinary metabolites.

Not all amino acids are same. Amino acids can be derived from a variety of sources, including plants, meats, fish and cartilage.

For arthritis treatment, the most compatible amino acid source is animal cartilage, including porcine, borvine cartilages and young chicken keel. Joint TLC is one of such products (www.holistictlc.com) that combines chondroitin, glucosamine and essential amino acids that promotes joint health, but this combination is still rare as most still use MSN in the place of cartilage derived amino acids, as MSN, for the marketer, is less expensive.

References:

1 Bradley JD, Flusser D, Katz BP, Schumacher HR Jr, Brandt KD, Chambers MA, Zonay LJ. A randomized, double-blind, placebo controlled trial of intravenous loading with S-adenosyltmethionine (SAM) followed by oral SAM therapy in patients with knee osteoarthritis. J Rheumatol 1994;21(5):905-11.

2 Barcelo HA, Wiemeyer JC, Sagasta CL, Macias M, Barreira JC. Experimental osteoarthritis and its course when treated with S-adenosyl-L-methionine. [Spanish} Rev Clin Esp 1990;187(20:74-78.

3 Konig B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med 1987;83(5A):89-94.

4 Baldessarini RJ. Neuropharmacology of S-adenosyl-L-methionine. Am J Med 1987;83(5A):95-103.

5 di Padova C. S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. Am J Med 1987;83(5A):60-5.

6 Flynn MA, Irvin W, Krause G. The effect of folate and cobalamin on osteoarthritic hands. J Am Coll Nutr 1994;13(4):351-6.

7 McCarty MF. The neglect of glucosamine as a treatment for osteoarthritis--a personal perspective. Med Hypotheses 1994;42(5):323-7.

8 Masse PG, Ziv I, Cole DE, Mahuren JD, Donovan SM, Yamauchi M, Howell DS. A cartilage matrix deficiency experimentally induced by vitamin B6 deficiency. Proc Soc Exp Biol Med 1998;217(1):97-103.

James Well consults to nutrition industry, specializing in Diet, Energy, Libido and Diabetes care and other related holistic products. He directs a research lab facility among other projects.


MORE RESOURCES:

KSL.com

Sen. Hatch disputes HBO story on dietary supplements
KSL.com
SALT LAKE CITY — Sen. Orrin Hatch is rebutting an HBO "Real Sports" story that ties him and a law he championed to several soldiers who died after taking dietary supplements sold on their bases. In a segment that aired Tuesday, correspondent Soledad ...
Op-ed: Supplements are regulated and safe, despite HBO's claimsSalt Lake Tribune
Senators urge Justice Department to enforce dietary supplement rulesSt George News

all 4 news articles »


Deseret News

Sen. Orrin Hatch calls HBO story on dietary supplements 'inaccurate'
Deseret News
Orrin Hatch is rebutting an HBO "Real Sports" story that ties him and a law he championed to several soldiers who died after taking dietary supplements sold on their bases. In a segment that aired Tuesday, correspondent Soledad O'Brien reported that ...
Senators Urge Justice Department to Step Up Actions against Adulterated ...Natural Products INSIDER (blog)

all 5 news articles »


Today.com

Are you getting enough? 5 important things to know about vitamins
Today.com
Once upon a time, the only source of vitamins was from food. Now shelves are filled with all kinds of vitamin supplements, with choices ranging from pills and chewables, to gummies and liquids. While the goal of taking vitamin supplements is to promote ...

and more »


Salt Lake Tribune (blog)

HBO report links Orrin Hatch's dietary supplement legislation to military ...
Salt Lake Tribune (blog)
In a segment that airs in Tuesday's episode of "Real Sports" (11 p.m., HBO), Soledad O'Brien reports on the deaths of several members of the U.S. military tied to dietary supplements sold at their bases — and ties those deaths to Sen. Orrin Hatch (R ...



Natural Products INSIDER (blog)

Keeping Sports Nutrition Supplements Clean
Natural Products INSIDER (blog)
With sports nutrition supplements, the end users are a dynamic bunch composed of well-informed—and sometimes well-misinformed—goal-oriented, diligent fitness enthusiasts. They have an insatiable appetite for peak performance through regimented ...



Philly.com (blog)

What I learned from taking Viviscal hair supplements for 190 days
Philly.com (blog)
My journey with Viviscal, the vitamin supplement specifically formulated for promoting hair growth, began in February. After reading how models and celebrities such as Lauren Conrad and Gwyneth Paltrow all used the product for beautiful, healthy hair, ...



New York Times (blog)

Well | Many Probiotics Taken for Celiac Disease Contain Gluten
New York Times (blog)
Now these experts say they may know why: More than half of the top-selling probiotic supplements they analyzed contained gluten, a protein found in wheat, barley and rye that is harmful to people with celiac disease. The authors of the study found ...
Probiotic Supplements May Contain Traces of GlutenHealthDay
'Gluten-free' probiotics often contain gluten, study findsFox News
Some 'Gluten-Free' Probiotics Are Not Really Gluten-Free: What You Should KnowTech Times
Science World Report
all 109 news articles »


Parade

Get Ready for Summer with 5 Healthy Supplements
Parade
When it comes to health products on the market, really, it's hit or miss. There are so many options; new brands, new products…drinks, shakes, supplements, YIKES, how do you get past the hype? Well, I tried a ton of new healthy offerings the last few ...



Fox News

Healthy woman's stroke linked to drug in sports supplement
Fox News
"This is the first time that we have been able to clearly link BMPEA supplement use with a very serious health consequence," said Dr. Pieter Cohen, a co-author of the report and an assistant professor of medicine at Harvard Medical School. [Wishful ...
Here's Why FDA Is Ordering BMPEA Supplements Off The MarketForbes
Amphetamine-like stimulant in dietary supplement linked to strokeCBS News
FDA Wants BMPEA Sports Supplements Pulled From Store ShelvesTech Times
Medical Daily -Science Times -Times Gazette
all 41 news articles »


Live Science

Cinnamon Supplements May Be Risky for People Taking Statins
Live Science
Taking cinnamon supplements could potentially be dangerous, especially for the millions of people who take statin drugs to lower their cholesterol, a new case report suggests. In the report, a 73-year-old woman developed the liver condition hepatitis ...


Google News


Advertisement



Section Site Map - Submit News - Feedback - Comments - Advertise with Us

Copyright © 2006 Luminati Inc. All rights reserved.