Bookmark Website  | Free Registration  | The Team
The Lounge  | Champions  | The Wire |  Schedule |  Audio  |  Arcade  |  The Top Ten  |  Historical  |  Email  |  Video

More Complete Arthritis Supplement


People accept arthritic disease as a 'natural part of the aging process', but sometimes the pain from osteoarthritis, rheumatoid arthritis, and over 100 other forms of arthritis so intolerable, prompting people to look for effective treatment.

Prescription drugs such as VIOXX, Bextra and Celebrex (arthritic painkillers) - and many other COX-2 inhibitors widely used for arthritic treatment - have been investigated following studies into their negative cardiovascular side effects. VIOXX alone has been linked to around 140,000 cases of coronary heart disease in the US since 1999.

More and more people look for alternative solutions for arthritis pain and more and more people are buying the combination of Glucosamine, Chondroitin Sulfate and MSN, as studies have shown that Glucosamine and Chondroitin help in the repair and maintenance of cartilage.

Both inflammation and oxidative stress function are primary degenerative mechanisms in the development and progression of osteoarthritis. While researchers believe that glucosamine inhibits inflammation and stimulates cartilage cell growth and chondroitin provides cartilage with strength and resilience, specific amino acids is also need for overall impact.

Amino acids are the building blocks that make up protein. Vitamins and minerals will not perform their specific functions effectively if the necessary amino acids are not present.

Three amino acids are critical to antioxidant, anti-inflammatory functions: cysteine, glutathione, and taurine.

Cysteine influences the synthesis of the antioxidant glutathione (GSH), which plays an important role in the inflammatory response by influencing the production of phagocytes.

Taurine acts as a specific scavenger for the hypochlorite ion, a free radical. Adequate levels of taurine naturally limit the degree of inflammation. When taurine is low, the inflammatory response is enhanced, commonly resulting in oxidative stress reactions.

Other amino acid imbalances may also impact the etiology of osteoarthritis - particularly methionine metabolism. Normally, B12 and folate are necessary for the body to metabolize homocysteine to methionine, the essential amino acid the body needs to produce S-adenosylmethionine. Numerous clinical trials have shown that S-adenosylmethionine can greatly reduce degenerative damage and symptoms of osteoarthritis in some patients, including related depression.

Imbalances of amino acids may also signal key deficiencies of vitamins and minerals integral to the musculoskeletal system. Experimental studies show that impaired cartilage structure can be induced by a vitamin B6 deficiency. Vitamin B6 triggers the transformation of the amino acid homocysteine to cystathionine and then to cysteine and its urinary metabolites.

Not all amino acids are same. Amino acids can be derived from a variety of sources, including plants, meats, fish and cartilage.

For arthritis treatment, the most compatible amino acid source is animal cartilage, including porcine, borvine cartilages and young chicken keel. Joint TLC is one of such products (www.holistictlc.com) that combines chondroitin, glucosamine and essential amino acids that promotes joint health, but this combination is still rare as most still use MSN in the place of cartilage derived amino acids, as MSN, for the marketer, is less expensive.

References:

1 Bradley JD, Flusser D, Katz BP, Schumacher HR Jr, Brandt KD, Chambers MA, Zonay LJ. A randomized, double-blind, placebo controlled trial of intravenous loading with S-adenosyltmethionine (SAM) followed by oral SAM therapy in patients with knee osteoarthritis. J Rheumatol 1994;21(5):905-11.

2 Barcelo HA, Wiemeyer JC, Sagasta CL, Macias M, Barreira JC. Experimental osteoarthritis and its course when treated with S-adenosyl-L-methionine. [Spanish} Rev Clin Esp 1990;187(20:74-78.

3 Konig B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med 1987;83(5A):89-94.

4 Baldessarini RJ. Neuropharmacology of S-adenosyl-L-methionine. Am J Med 1987;83(5A):95-103.

5 di Padova C. S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. Am J Med 1987;83(5A):60-5.

6 Flynn MA, Irvin W, Krause G. The effect of folate and cobalamin on osteoarthritic hands. J Am Coll Nutr 1994;13(4):351-6.

7 McCarty MF. The neglect of glucosamine as a treatment for osteoarthritis--a personal perspective. Med Hypotheses 1994;42(5):323-7.

8 Masse PG, Ziv I, Cole DE, Mahuren JD, Donovan SM, Yamauchi M, Howell DS. A cartilage matrix deficiency experimentally induced by vitamin B6 deficiency. Proc Soc Exp Biol Med 1998;217(1):97-103.

James Well consults to nutrition industry, specializing in Diet, Energy, Libido and Diabetes care and other related holistic products. He directs a research lab facility among other projects.


MORE RESOURCES:

Antioxidant Supplements Don't Fight Cancer, Research Suggests
Huffington Post
In the study, researchers found that male smokers who took of 20-milligram supplements of beta-carotene (an antioxidant) daily for five to eight years had an 18 percent increased rate of lung cancer, and an 8 percent increased mortality rate, compared ...



FDA warns of generic Viagra hidden in "natural" OMG supplement: Tainted ...
The Plain Dealer
The FDA is warning consumers that O.M.G., a "natural" sexual health supplement sold for men, contains undisclosed sildenafil, or generic Viagra. The pharmaceutical ingredient makes the supplement dangerous, particularly to anyone taking nitrates for ...



velonews.competitor.com

Buyer Beware: Are Your Supplements Tainted?
velonews.competitor.com
It's not overly cynical to “expect” any doping athlete to blame a contaminated dietary supplement for his or her positive dope test, but WADA doesn't let athletes off the hook for “accidents;” even when some supplements have clearly been found to ...



News One

Don't Take This If You Have High Blood Pressure
News One
According to Mayo Clinic, if you've been diagnosed with high blood pressure, you need to re-think the supplements you're taking. Why? While supplements may be labeled “natural” and don't generally need a prescription, they can affect the body in many ...



CNN

Don't be fooled by dietary supplement claims
CNN
(CNN) -- Recently, the Senate Subcommittee on Consumer Protection successfully ignited a public discussion about dietary supplements. It's about time. But this is only a first step, and of no substantive value without continued careful objective and ...

and more »


Quartz

Fish oil supplements may reduce cognitive decline, unless you're already at ...
Quartz
Fish oil supplements have a slippery reputation when it comes to preventing cognitive decline, the hallmark symptom of Alzheimer's disease. Studies have provided ambiguous results, promoting recommendations founded more on faith than evidence.
Fish Oil Supplements May Protect Against Alzheimer'sHuffington Post
Fish Oil Supplements Reduce Cognitive Decline in Older Adults, Study FindsHeadlines & Global News
Fish Oil Boosts Brain PowerYahoo Health
University Herald -Science World Report -Science 2.0
all 119 news articles »


Potassium Supplements May Help Some Heart Failure Patients
The Jewish Voice
Potassium supplements might boost the survival of heart failure patients who are already taking diuretic drugs, a new study suggests. Nearly 5.8 million Americans have heart failure. As doctors explain it, excess fluid can accumulate in the body when ...



Health Column: Get your mojo going with energy supplements
Glenwood Springs Post Independent
Most of us could use a bit more of it. Some people suffer from a complete lack of it. Athletes burn a lot with activity and we all need it to maintain a sharp mental state. What I'm referring to is energy, and in order to move and think, we need it ...



Telegraph.co.uk

The Beauty Supplement: supplements for sunburnt skin
Telegraph.co.uk
Scientists often agree that moderate sun exposure can make us feel better as it encourages the production of vitamin D3, crucial for hundreds of processes within our bodies. And science aside, we all feel better with a little sun on our backs. However ...

and more »


Mr. Olympia, Phil Heath, Launches A New Line Of Nutrition Supplements
Forbes
Becoming Mr. Olympia is no easy feat. It takes hard work, dedication, tough mentality, a serious workout plan, a solid nutrition plan and the appropriate supplements. If anyone knows anything about becoming Mr. Olympia, it's Phil Heath. The current ...

and more »

Google News


Advertisement



Section Site Map - Submit News - Feedback - Comments - Advertise with Us

Copyright © 2006 Luminati Inc. All rights reserved.