Promoter Frank Maloney is planning a clash between close pals Rendall Munroe and Jason Booth this summer.
The mouth-watering fight will take place providing Booth is successful in his European super-bantamweight clash against Kiko Martinez in Madrid on April 15.
Munroe returns to action an eight rounder against Chris Riley at Rainton Meadows Arena, Houghton-le-Spring, on April 9 - his first fight since losing on points to WBC 122lb champion Toshiaki Nishioka in October.
Provided the Leicester binman beats Riley he expects to become official challenger for the European crown he once held.
Maloney explained: "It is a fight that Jason and Rendall have been reluctant to talk about let alone contemplate.
"They except that business is business and there is now a real possibility that will have to face each other in the near future.
"Rendall wants to win back his old crown and Jason will not want to relinquish once he beats Martinez.
"And with both boys from the East Midlands it would attract tremendous interest in the region."
In the Houghton-le-Spring bill topper, Darlington's Stuart Hall (10-0-1) risks his British bantamweight title against Liverpool's John Donnelly (12-1).
Hall won the British crown against Ian Napa and will win a Lonsdale belt outright if he makes a successful third defence against Scouser Donnelly.