|The Lounge | Champions | The Wire | Schedule | Audio | Arcade | The Top Ten | Historical | Email | Video|
Whey Protein Importance
Studies on whey demonstrate it's an even better protein supplement than previously thought. Although whey protein's health benefits have only recently been elucidated, the use of whey protein for medicinal purposes has been prescribed since the time of Hippocrates. In fact, there are two ancient proverbs from the Italian city of Florence that say, "If you want to live a healthy and active life, drink whey," and, "If everyone were raised on whey, doctors would be bankrupt."
In previous issues, we've chronicled the extensive research showing the many potential health benefits of whey protein concentrate. The majority of that research was done in the 1980s and early 1990s, and was extremely persuasive. Scientists have continued their research on whey proteins with even more impressive results. What follows is some of the more current, interesting and useful research on whey proteins.
Whey and Cancer
Additional studies have been done on animals regarding cancer-causing chemicals to see what effects whey protein concentrate would have on cancer prevention or treatment. Scientists fed rats various proteins and then subjected them to the powerful carcinogen dimethylhydrazine.
As with the previous research, the rats fed whey protein concentrate showed fewer tumors and a reduced pooled area of tumors (tumor mass index). The researchers found whey protein offered "considerable protection to the host" over that of other proteins, including soy.
1. Even more exciting, in vivo research on cancer and whey showed whey protein concentrate inhibited the growth of breast cancer cells at low concentrations (Baruchel S. and Vaiu G., Anti Cancer Research, 1996). Finally, and most importantly, a fairly recent clinical study with cancer patients showed a regression in some patient's tumors when fed whey protein concentrate at 30 grams per day.
2. Whey and Glutathione
This new research using whey protein concentrate led researchers to an amazing discovery regarding the relationship between cancerous cells, glutathione (GSH) and whey protein concentrate. It was found that whey protein concentrate selectively depletes cancer cells of their glutathione, thus making them more susceptible to cancer treatments such as radiation and chemotherapy.
It has been found that cancer cells and normal cells will respond differently to nutrients and drugs that affect glutathione status. What is most interesting to note is the fact that the concentration of glutathione in tumor cells is higher than that of the normal cells that surround it. This difference in glutathione status between normal cells and cancer cells is believed to be an important factor in cancer cells' resistance to chemotherapy.
As the researchers put it, "Tumor cell GSH concentration may be among the determinants of the cytotoxicity [poisonous to cells] of many chemotherapeutic agents and of radiation, and an increase in GSH concentration appears to be at least one of the mechanisms of acquired drug resistance to chemotherapy."
They further state, "It is well-known that rapid GSH synthesis in tumor cells is associated with high rates of cellular proliferation. Depletion of tumor GSH in vivo decreases the rate of cellular proliferation and inhibits cancer growth."
The problem is, it's difficult to reduce glutathione sufficiently in tumor cells without placing healthy tissue at risk and putting the cancer patient in a worse condition. What is needed is a compound that can selectively deplete the cancer cells of their glutathione, while increasing, or at least maintaining, the levels of glutathione in healthy cells.
This is exactly what whey protein appears to do. In this new research it was found that cancer cells subjected to whey proteins were depleted of their glutathione, and their growth was inhibited, while normal cells had an increase in GSH and increased cellular growth.
These effects were not seen with other proteins. Not surprisingly, the researchers concluded, "Selective depletion of tumor GSH may in fact render cancer cells more vulnerable to the action of chemotherapy and eventually protect normal tissue against the deleterious effects of chemotherapy." The exact mechanism by which whey protein achieves this is not fully understood, but it appears that it interferes with the normal feedback mechanism and regulation of glutathione in cancer cells.
It is known that glutathione production is negatively inhibited by its own synthesis. Being that baseline glutathione levels in cancer cells are higher than that of normal cells, it is probably easier to reach the level of negative-feedback inhibition in the cancer cells' glutathione levels than in the normal cells' glutathione levels.
Whey and LDL Cholesterol
The positive health benefits of whey protein concentrate does not end with its effects on immunity and cancer prevention and treatment. Whey protein concentrate also was found to be a potent inhibitor of oxidized low density lipoprotein cholesterol. Current research suggests that the conversion of LDL to oxidized LDL is the trigger that leads to atherogenesis... the formation of the plaque and lesions associated with atherosclerosis.
Therefore, any substance that prevents the oxidation of LDL is thought to be anti-atherogenic. Though animal-based proteins have traditionally been implicated as being pro-atherogenic, whey proteins appear to be an exception to the rule. whey protein is made up of several minor and major fractions, such as beta-lactoglobulin, alpha-lactalbumin, albumin, lactoferrin and immunoglobulin. It was discovered that the minor constituent responsible for the ability of whey protein concentrate to prevent the oxidation of LDL appears to be the lactoferrin fraction of the protein.
3. Lactoferrin In Whey
When the lactoferrin was removed from the protein, the ability of the whey-protein concentrate to prevent LDL oxidation was greatly reduced, leading the researchers to speculate, "Our results suggest that LF (lactoferrin) is the main factor responsible for the inhibitory effect of whey protein (on LDL) and it may function synergistically together with other factors in the whey protein, for example, alpha-lactalbumin."
Another study using rats examined the effects of whey protein concentrate and casein on cholesterol and the risk factors of heart disease. Though casein (another milk-based protein commonly used in research) is known to raise cholesterol in humans and animals, whey protein has the opposite effect, leading the researchers to note, "At the high dietary protein level [300 gram per kilogram of feed] , whey protein significantly lowered plasma and liver cholesterol and also plasma triacylglycerols."
4. The cholesterol-lowering effects of whey protein concentrate in this study also was associated with a reduction in LDL cholesterol. Most interesting was the fact that this effect on cholesterol was not seen when the animals were fed amino acid mixtures that simulated whey protein, so it is clear that there are properties within the whey that have these effects beyond that of its amino acid profile.
Whey and Bone Growth
Finally, whey protein appears to play a direct role in bone growth. Researchers found that rats fed whey protein concentrate showed increased bone strength and bone protein such as collagen. This discovery led researches to test whether or not whey protein directly stimulated osteoblast (bone cell) growth in vitro.
Whey protein was found to stimulate, dose dependently, total protein synthesis, DNA content, and increased hydroxyproline contents of bone cells.
5. It should be noted that not all whey protein concentrates are created equal. Processing whey protein to remove the lactose and fats without losing its biological activity takes special care by the manufacturer. The protein must be processed under low temperature and low acid conditions so as not to "denature" the protein. Maintaining the natural state of the protein is essential to its biological activity. These research findings, combined with the previous decade of study on whey protein, should convince anyone that whey protein concentrate is truly the life-extension protein.
Higher Glutathione Levels and Whey
A decade-and-a-half of findings on the benefits of whey protein are far-reaching.
Previous Studies Include The Following:
Whey protein concentrate dramatically raises glutathione levels. Glutathione is an essential water-soluble antioxidant in the body that protects cells and serves as a primary detoxifier of harmful compounds such as peroxides, heavy metals, carcinogens and other toxins.
Glutathione also is intimately tied to immunity, and reduced glutathione levels have been associated with disease such as AIDS, atherosclerosis, Alzheimer's disease and Parkinson's disease, to name only a few. In fact, glutathione levels appear to be one way of modulating immunity.
6. Whey protein concentrate was found to consistently raise this extremely important immune stimulating antioxidant beyond that of any protein studied (including soy) to higher than normal levels in multiple animal studies.
7. A small pilot study with HIV-positive men who were fed whey protein concentrate found dramatic increases in glutathione levels of all the study participants, with two out of three men reaching their ideal body weight.
8. In fact, there have been several U.S. and international patents granted for the treatment of AIDS and improving immunity with whey protein concentrates.Whey protein improves immune function and fights infections. Animals fed whey protein concentrate consistently showed dramatic enhancement of both the humoral and cellular immune response to a variety of immune challenges, such as salmonella, streptococcus pneumonia 9 and extreme cancer-causing chemicals. This effect on immunity was not seen with other proteins. So proof Whey protein concentrate fights cancer!!
Catholic Charities Senior Nutrition Program will not have to reduce days in ... - Imperial Valley Press
Practical Nutrition: Enjoy hot cocoa add-ins without too many extra calories - Richmond Times Dispatch (blog)
Mannatech's patent-pending glyconutrients complex, Ambrotose, is perhaps the greatest wellness discover in the last 50 years. By understanding it, you are in a better position to help others realize that they too would have this phenomenal nutrient Ambrotose complex working on their behalf as well.
Balanced Diet: Know More on Healthy and Nutritional Balanced Diet!
In this fast paced world, good nutrition may sound very simple but it is indeed really difficult to practice it. We eat too many processed foods or we tend to miss some meals.
There is No Miracle Cure for Arthritis, but Improving Your Diet can Help
Arthritis - if you suffer from this illness, I don't have to tell you how bad it is. If you don't suffer from it yet, keep reading - I want to make sure you will do everything in your power to prevent yourself from getting it.
The Best Protein Powder
What is the best protein powder to buy? I get this question all the time, and really, there is no best protein - many are very good for different reasons! In my opinion, it is futile and possibly detrimental to stick to only one brand for the following reasons:a) I always recommend that you cycle your supplements so that your body does not get used to them thereby decreasing their effect,b) for variety sakes alone, it breaks the monotony and allows you to try different brands,c) to take advantage of the unique qualities offered by various brands, andd) it is a good idea to switch the powders you use on a frequent basis to not develop any food intolerances or even worse allergies (I have an article coming out on this subject in the near future.) A blend that combines various protein sources (i.
The Glycemic Index and Dieting
The field of nutrition is awash with charts, tables, diagrams, models, acronyms, and abbreviations; more than the average person can memorize. As such, one often comes across someone who has simply burnt out trying to keep track of how much to eat, when to eat it, how to find the calories from fat, the RDI, the DV, and so on.
Antioxidants - Your Best Defense Against Disease and Aging
Studies support the benefits of eating a diet rich in fruits and vegetables. This is due to their high antioxidant value.
The New Food Pyramid: Another Attempt At Providing Easy Answers
The Food Pyramid, first introduced to the US in 1992, just experienced a major overhaul. Why? Perhaps proper education about nutrition isn't as easy as picking out food from a colorful chart.
Fruit for Breakfast - The Secret to a Healthy Life
Do you want more energy? How about more of the vitamins, minerals and enzymes that your body craves? Try eating fruit for breakfast! Fresh fruit - apples, grapefruit, strawberries, cherries, oranges, kiwi, melon, and grapes all count. In fact, any fruit works - and there are so many to choose from.
10 Flaxseed Facts to Improve Your Nutrition
Flaxseeds may be the smallest seeds you will find in any health food store, but there is nothing little about their enormous contribution to our overall health. Discovered in 5,000 BC, these little brown seeds were worshiped for their magical properties, such as healing the intestines, skin conditions, improving energy, and overall health.
Help Your Heart Grow
I turned into my parents' driveway in Maryland and parked the car. Before I could even step out and close the door, Mom flew out of the backyard, gesturing frantically.
Simple Food and Diet Nutrition Remedies for Your Common Health Ailments
You are what you eat is a simple, time tested adage that still holds true today. There are non-medical remedies that can help with many of today's most common illnesses and conditions.
Autism and Nutritional Supplements
Unfortunately, it has been proved beyond doubt that a large percentage of the United States population suffers from nutritional deficiency. Studies show, 30% of the general population has a marginal level of Vitamin C and 15% are Vitamin C deficient.
Beginning an Alkaline Diet: The Basic Principles - Start Alkalizing Today!
Each and every person living in the UK is facing a myriad of health and lifestyle challenges every day. We are constantly being fed new information about what is healthy and what is unhealthy while thousands of us try to deal with problems ranging from obesity to fatigue to life threatening diseases.
Dietary Sources of Glutathione
DIETARY SOURCES OF GLUTATHIONE: Glutathione (GSH) is an antioxidant and detoxifying agent whose protective role has been demonstrated in numerous clinical studies. GSH is synthesized rapidly in the liver, kidneys, and other tissues of the body, including the gastrointestinal tract.
Four Important Nutrients - Vitamin E, Selenium, Sodium and Potassium - For Good Health
Vitamin EThere has been a lot of controversy about vitamin E lately. In the news last month, the news media was pushing a story that "Vitamin E can cause you to die.
Cranberry Juice To The Rescue
Cranberry juice was first made by American settlers in 1683. It is a love it or hate it beverage.
Our Livers Need for Water
Although many realize that the liver has its own cleansing system, it does need help - as it cannot maintain its healthy state if its being abused. Abuse occurs when too much of the wrong foods are entering the body.
The Importance of Good Nutrition in Keeping Your Smile Beautiful and Your Mouth Healthy
A beautiful smile and healthy mouth actually can come from in addition to regular brushing and flossing a daily diet that does not lack the essential vitamins and minerals that make vital contributions to a person's oral health. Many people overlook the importance of good nutrition in keeping their smile beautiful and their mouth healthy.
7 Bad Eating Habits You Should Change Immediately
People are obsessed with dieting and weight loss! Don't believeme? Just tune-in to any source of advertising..
What Is an Essential Fat?
You may have heard that essential fats are an important aspect tomaintaining the health of your body. But what exactly are they?Basically, there are two truly essential fatty acids, Linoleic and Linolenic.
Section Site Map - Submit News - Feedback - Comments - Advertise with Us
Copyright © 2006 Luminati Inc. All rights reserved.