Human idiopathic thermogenesis (burning of unknown origin) is a condition that is not very well understood by medical practitioners. The pathophysiology has not been able to be demonstrated conclusively, but there is a strong immunological and drug correlation; antibiotics, anticonvulsants, and nonsteroidal anti-imflammatory drugs are the most common causative agents.
Classifications of Idiopathic Thermogenesis in the Body
(from least to most severe)
1. Erthema exsudativum multiforme majus (EEMM)
Skin detachment typical and/or atypical; involvement mostly on limbs
2. Stevens-Johnson Syndrome (SJS)
Skin detachment with atypical target lesions and/or purpuric mascules in wide dissemination
3. SJS/TEN overlap
Skin detachment between 10% and 30% of the body surface area with atypical target lesions and/or macules in wide dissemination
4. Toxic epidermal necrolysis (TEN) with maculae
Skin detachment >30% of the body surface area, atypical target lesions and/or macules
5. Toxic epidermal necrolysis (TEN) on large erythema
Skin detachment >10% of the body surface area without any targets or purpuric macules
6. Superhyperthermic carbonization (SHC)
Deep burning of tissues and/or bones often resulting in complete carbonization of body; targets areas of greatest infirmity
These condiotions share similarities :
-Occurs most frequently in winter followed by spring (SJS and SHC data)
-Predominate in Caucasians
-Gender nonspecific
-Very rare with potential for misdiagnosis; etiology unknown
-Older more likely to be effected with severe and/or fatal cases
-Precipitated by disease and/or infirmity often linked to elevated free radicals
-Precipitated by various medication usages and/or alcohol consumption
-Often precipitated by increased exposure to ionizing radiation (cranial in TEN; total body SHC)
-Radiation aftereffects noted on body (TEN) and/or in surroundings (SHC)
People who experienced this phenomenon:
While the less severe cases of i.t. are well documented within medical literature, the most severe (spontaneous human combustion) has yet to be a labeled bona fide condition.
Spontaneous human combustion - fact or fiction?
http://www.journaloftheoretics.com/A...rd%20IT1-3.pdf
Classifications of Idiopathic Thermogenesis in the Body
(from least to most severe)
1. Erthema exsudativum multiforme majus (EEMM)
Skin detachment typical and/or atypical; involvement mostly on limbs
2. Stevens-Johnson Syndrome (SJS)
Skin detachment with atypical target lesions and/or purpuric mascules in wide dissemination
3. SJS/TEN overlap
Skin detachment between 10% and 30% of the body surface area with atypical target lesions and/or macules in wide dissemination
4. Toxic epidermal necrolysis (TEN) with maculae
Skin detachment >30% of the body surface area, atypical target lesions and/or macules
5. Toxic epidermal necrolysis (TEN) on large erythema
Skin detachment >10% of the body surface area without any targets or purpuric macules
6. Superhyperthermic carbonization (SHC)
Deep burning of tissues and/or bones often resulting in complete carbonization of body; targets areas of greatest infirmity
These condiotions share similarities :
-Occurs most frequently in winter followed by spring (SJS and SHC data)
-Predominate in Caucasians
-Gender nonspecific
-Very rare with potential for misdiagnosis; etiology unknown
-Older more likely to be effected with severe and/or fatal cases
-Precipitated by disease and/or infirmity often linked to elevated free radicals
-Precipitated by various medication usages and/or alcohol consumption
-Often precipitated by increased exposure to ionizing radiation (cranial in TEN; total body SHC)
-Radiation aftereffects noted on body (TEN) and/or in surroundings (SHC)
People who experienced this phenomenon:
Two years prior to this date, in February of 1996, she experienced an explosion adjacent to her left shoulder blade which created a dark smoke that filled her kitchen. She reported feeling "something from the base of my back going up my back" (40). Her back remained hot and red for only fifteen minutes at which time her skin returned to normal.
One patient diagnosed with TEN described her experience, "First I just had the rash on my face, arms, and legs, and then it was all over, even my lips and my eyes. I got these blisters like I was in one of those horror movies after a nuclear explosion
Spontaneous human combustion - fact or fiction?
http://www.journaloftheoretics.com/A...rd%20IT1-3.pdf
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