Well for me, naturally it would be Resident Evil 7 and Borderlands III. Those two have been the only series I turn my PS3 on for, for the past 4 years. Before Borderlands, I was a strictly Resident Evil and MLB[989 Sports] and then MLB The Show. I have 13 other PS3 games which I don't even use. Dead Space a very far 3rd after RE and BL.
I'm really considering getting an XBox 360 just for the Gears of War series.