I doubt this KO will affect Manny the way Oscar thinks, he was KO'd and dropped many times in his early career, that is usually when it affects a fighter mentally and changes their style to be more cautious.
Pacquiao didn't change after those knockdowns and KO's and still continued to fight wild and aggressive.
The Post fight interview should give you an indicator of it, he was smiling and accepted the defeat. He wasn't like Ricky Hatton, all weak and depressed and self pity. Pacman even told Ariza why is everyone so sad? this is boxing stuff happens, people get caught and lose. Ariza was even shocked that Pacman wasn't even bothered by the KO, he said the only reason Pac feels bad is that people feel bad.
He said something to the tune of if you are scared to lose than don't fight.
Pacquiao is not your typical fighter, he will be the same in his next fight he might even be more aggressive because he wanted to get back in the ring on April but he was suspended medically for 120 days, his chin might not be the same though.