By Carlos Boogs

WBC heavyweight champion Deontay Wilder is shaking his head at Tyson Fury's withdrawal from next month's rematch with Wladimir Klitschko. The fight was called off on Friday for a second time with the Briton ruled "medically unfit".

The fight was due to be held on Oct. 29 in Manchester, having been originally postponed in July when Fury suffered an ankle injury.

Fury was ringside for Wilder's defense in January at the Barclays Center in Brooklyn. The two heavyweight went face to face in the ring and had to be separated after a tense confrontation.

"Tyson has this week been declared medically unfit to fight," his promoters Hennessy Sports said in a statement without elaborating. "Medical specialists have advised that the condition is too severe to allow him to participate in the rematch and that he will require treatment before going back into the ring.

"We and Tyson wish to express our sincerest apologies to all those concerned with the event and all the boxing fans who had been looking forward to the rematch. Tyson is understandably devastated by the development. We will be making a further statement in due course. Until then we ask that Tyson and his family be given the privacy and the space he needs to recover during this difficult time."

Previous champion Klitschko, who had ruled the heavyweight division for a decade, raised doubts about the fight going ahead during a news conference earlier this month. Fury, who has been charged over anti-doping violations but denies any wrongdoing, caused a huge shock when he registered a unanimous points victory over Klitschko in Duesseldorf in November.

The unbeaten Briton, who has courted controversy throughout his career, was charged by UK Anti-Doping (UKAD) in June after a urine sample taken nine months before he beat Klitschko showed traces of the banned substance nandrolone.

Fury's legal team said the result of tests on the samples in March and May 2015 were contradictory and launched High Court proceedings against UKAD. A provisional suspension was lifted pending the result of an independent hearing.

"I really think about it man... its very sad and disappointing to see a champion not willing to perform at this level. There is no self discipline. One day soon there will be one name, one face and one champion, and that will be Deontay Wilder. I think it's time to unify. That way you don't have to worry about all this mishap. Its just sad, a champion not in shape," Wilder told At The Fights: Monday and Friday 6-8pm EST on SiriusXM Rush 93

"I guess he's at his all-time high in his career and he did what he wanted to do. I don't really think he has anymore feelings towards this. I don't think he really cares anymore. He wants to beat the Klitschkos. He accomplished his ultimate goal. I don't think he really cares. It bothers me a lot because I'm very disciplined in my craft and what I do."